Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9920430 | 0.82 | ALDH1A1 (0.47) | KDM4ECYP1A2CYP2C19CYP2C9L3MBTL1 | |
| SCHEMBL22372303 | 0.71 | CYP1A2 (0.39) | KDM4ECYP1A2CYP2C19CYP2C9L3MBTL1 | |
| SCHEMBL18605681 | 0.70 | CA12 (0.37) | KDM4EL3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL29111666 | 0.69 | LMNA (0.54) | KDM4EALDH1A1SMN1; SMN2LMNAGAA | |
| SCHEMBL22372125 | 0.68 | TSHR (0.46) | KDM4ECYP1A2CYP2C19CYP2C9L3MBTL1 | |
| SCHEMBL1625704 | 0.68 | POLB (0.50) | KDM4ECYP1A2L3MBTL1ALDH1A1MEN1 | |
| SCHEMBL22372238 | 0.67 | L3MBTL1 (0.40) | KDM4ECYP1A2CYP2C19CYP2C9L3MBTL1 | |
| SCHEMBL5246921 | 0.67 | ALDH1A1 (0.40) | CYP2C19CYP2C9ALDH1A1MEN1KMT2A | |
| SCHEMBL9248449 | 0.67 | KDM4E (0.38) | KDM4EL3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL10456119 | 0.66 | KDM4E (0.63) | KDM4EALDH1A1KMT2ASMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636135-A1 | TRIAZOLE COMPOUNDS | Japat Ltd (CH) | 1995-02-01 | — | — | EP | disclosed |
| WO-1992019629-A1 | TRIAZOLE COMPOUNDS | JAPAT LTD. (CH) | 1992-11-12 | — | — | WO | disclosed |