Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS15 | P98073 | 4/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | F7 | P08709 | 1/20 | 0.34 |
| ▸ | F3 | P13726 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9255921 | 0.92 | ITGB3 (0.40) | ITGB3ITGA2BF2F7F3 | |
| SCHEMBL9251469 | 0.87 | TMPRSS15 (0.37) | TMPRSS15ITGB3ITGA2BF10F2 | |
| SCHEMBL9252066 | 0.85 | TMPRSS15 (0.36) | TMPRSS15ITGB3ITGA2BF10 | |
| SCHEMBL9571132 | 0.85 | ITGB3 (0.36) | TMPRSS15ITGB3ITGA2BF10 | |
| SCHEMBL9253812 | 0.85 | TMPRSS15 (0.35) | TMPRSS15ITGB3ITGA2BF10F2 | |
| SCHEMBL9246322 | 0.85 | TMPRSS15 (0.35) | TMPRSS15ITGB3ITGA2BF10F2 | |
| SCHEMBL9255320 | 0.83 | TMPRSS15 (0.35) | TMPRSS15ITGB3ITGA2BF10 | |
| SCHEMBL9251312 | 0.78 | TMPRSS15 (0.40) | TMPRSS15ITGB3ITGA2BF10 | |
| SCHEMBL9256518 | 0.78 | ITGB3 (0.40) | ITGB3ITGA2BF2F7F3 | |
| SCHEMBL9251108 | 0.78 | ITGB3 (0.40) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5434150-A | Anticoagulants, cardiovascular disorders | DR. KARL THOMAE GMBH (DE) | 1995-07-18 | — | — | US | disclosed |
| EP-0531883-A1 | Condensed 5-membered ring heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-03-17 | — | — | EP | disclosed |