Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.67 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA7 | P43166 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9252446 | 0.80 | MAPT (0.67) | GAAMAPTLMNAKDM4EALDH1A1 | |
| SCHEMBL9246309 | 0.78 | KDM4E (0.58) | GAAPOLBNPC1RAB9AMAPT | |
| SCHEMBL9251955 | 0.78 | MAPT (0.66) | GAACA2MAPTMEN1KMT2A | |
| SCHEMBL9251859 | 0.78 | PRKCI (0.54) | GAANPC1RAB9AMAPTLMNA | |
| Acetic Acid SCHEMBL9251660 | 0.76 | MAPT (0.57) | GAAMAPTKDM4EALDH1A1HSD17B10 | |
| Hydrochloric Acid SCHEMBL9246062 | 0.76 | MAPT (0.75) | GAACA1CA2CA7CA9 | |
| SCHEMBL30597452 | 0.73 | GAA (0.79) | GAACA1CA2CA7CA9 | |
| SCHEMBL4488518 | 0.73 | GAA (0.79) | GAACA1CA2CA7CA9 | |
| SCHEMBL28689186 | 0.73 | GAA (0.79) | GAACA1CA2CA7CA9 | |
| SCHEMBL9255324 | 0.73 | ALDH1A1 (0.53) | GAAPOLBTSHRMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5434150-A | Anticoagulants, cardiovascular disorders | DR. KARL THOMAE GMBH (DE) | 1995-07-18 | — | — | US | disclosed |