Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.66 |
| ▸ | GAA | P10253 | 2/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.66 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9252446 | 0.90 | MAPT (0.67) | MAPTALDH1A1KDM4EGAAHSD17B10 | |
| SCHEMBL9246309 | 0.85 | KDM4E (0.58) | MAPTALDH1A1KDM4EGAAHSD17B10 | |
| Acetic Acid SCHEMBL9251660 | 0.84 | MAPT (0.57) | MAPTALDH1A1KDM4EGAAHSD17B10 | |
| SCHEMBL9245378 | 0.83 | HCAR3 (0.65) | MAPTALDH1A1KDM4EGAAPTGER4 | |
| SCHEMBL1468005 | 0.82 | PTGER4 (0.69) | MAPTALDH1A1KDM4EGAAHSD17B10 | |
| SCHEMBL9251859 | 0.82 | PRKCI (0.54) | MAPTALDH1A1KDM4EGAAHSD17B10 | |
| Hydrochloric Acid SCHEMBL9256210 | 0.79 | MAPT (0.51) | MAPTALDH1A1KDM4EGAAHSD17B10 | |
| SCHEMBL9252717 | 0.78 | GAA (0.67) | MAPTALDH1A1KDM4EGAAHSD17B10 | |
| SCHEMBL15320652 | 0.77 | PTGER4 (0.76) | MAPTALDH1A1KDM4EGAAHSD17B10 | |
| SCHEMBL2955366 | 0.76 | L3MBTL1 (0.63) | MAPTALDH1A1L3MBTL1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5434150-A | Anticoagulants, cardiovascular disorders | DR. KARL THOMAE GMBH (DE) | 1995-07-18 | — | — | US | disclosed |