Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MLYCD | O95822 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9252446 | 0.86 | MAPT (0.67) | KDM4EALDH1A1MAPTGAAHSD17B10 | |
| SCHEMBL9251955 | 0.85 | MAPT (0.66) | KDM4EALDH1A1MAPTGAAHSD17B10 | |
| SCHEMBL9246073 | 0.84 | NPC1 (0.58) | ALDH1A1MAPTGAARAB9ANPC1 | |
| Acetic Acid SCHEMBL9251660 | 0.83 | MAPT (0.57) | KDM4EALDH1A1MAPTGAAHSD17B10 | |
| SCHEMBL9246132 | 0.81 | LMNA (0.48) | KDM4EALDH1A1MAPTGAAHSD17B10 | |
| SCHEMBL9252717 | 0.78 | GAA (0.67) | KDM4EALDH1A1MAPTGAAHSD17B10 | |
| SCHEMBL9251859 | 0.78 | PRKCI (0.54) | KDM4EALDH1A1MAPTGAAHSD17B10 | |
| SCHEMBL9255324 | 0.78 | ALDH1A1 (0.53) | KDM4EALDH1A1MAPTGAAHSD17B10 | |
| SCHEMBL9335711 | 0.76 | BRD4 (0.53) | KDM4EMAPTHDAC6RAB9AHDAC1 | |
| Hydrochloric Acid SCHEMBL9256210 | 0.75 | MAPT (0.51) | KDM4EALDH1A1MAPTGAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5434150-A | Anticoagulants, cardiovascular disorders | DR. KARL THOMAE GMBH (DE) | 1995-07-18 | — | — | US | disclosed |