Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.49 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | OPRL1 | P41146 | 11/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 10/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 10/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 9/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | CACNA2D1 | P54289 | 3/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.40 |
| ▸ | CACNB1 | Q02641 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9253403 | 0.93 | OPRL1 (0.54) | KDM4ES1PR4ALDH1A1HSP90AA1MAPT | |
| SCHEMBL9258075 | 0.91 | OPRM1 (0.54) | KDM4ES1PR4ALDH1A1HSP90AA1MAPT | |
| SCHEMBL9254374 | 0.84 | OPRM1 (0.59) | KDM4EALDH1A1MAPTHTTSMN1; SMN2 | |
| SCHEMBL9247567 | 0.81 | OPRM1 (0.49) | OPRL1OPRM1OPRK1OPRD1CNR1 | |
| SCHEMBL9250409 | 0.81 | OPRM1 (0.49) | ALDH1A1OPRL1OPRM1OPRK1OPRD1 | |
| SCHEMBL9250178 | 0.76 | KCNH2 (0.52) | KDM4EALDH1A1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL9257134 | 0.73 | OPRM1 (0.54) | ALDH1A1MAPTSMN1; SMN2NPSR1OPRL1 | |
| SCHEMBL9250914 | 0.73 | OPRM1 (0.54) | KMT2AOPRL1OPRM1OPRK1OPRD1 | |
| SCHEMBL5011686 | 0.73 | MEN1 (0.56) | KMT2AOPRL1OPRM1OPRK1OPRD1 | |
| SCHEMBL9253761 | 0.73 | OPRM1 (0.54) | ALDH1A1OPRL1OPRM1OPRK1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5470851-A | Antihistamine, anticoagulants | SANKYO COMPANY, LIMITED (JP) | 1995-11-28 | — | — | US | disclosed |
| EP-0463873-A1 | Thiazolidinecarboxylic acid amide derivatives having anti-allergic activity, their preparation and their use | Sankyo Company Limited (JP) | 1992-01-02 | — | — | EP | disclosed |