Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 6/20 | 0.54 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.54 |
| ▸ | OPRL1 | P41146 | 6/20 | 0.54 |
| ▸ | MCOLN2 | Q8IZK6 | 9/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MC4R | P32245 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9250409 | 0.93 | OPRM1 (0.49) | OPRM1OPRD1OPRK1OPRL1MCOLN2 | |
| SCHEMBL9256147 | 0.90 | OPRM1 (0.59) | OPRM1OPRD1OPRK1OPRL1MCOLN2 | |
| SCHEMBL9250914 | 0.85 | OPRM1 (0.54) | OPRM1OPRD1OPRK1OPRL1MCOLN2 | |
| SCHEMBL3283029 | 0.82 | CYP2D6 (0.40) | OPRM1OPRD1OPRK1OPRL1MCOLN2 | |
| SCHEMBL9258176 | 0.78 | OPRM1 (0.54) | OPRM1OPRD1OPRK1OPRL1MC4R | |
| SCHEMBL9253403 | 0.78 | OPRL1 (0.54) | OPRM1OPRD1OPRK1OPRL1ALDH1A1 | |
| SCHEMBL3426974 | 0.78 | MEN1 (0.56) | OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL9257361 | 0.75 | OPRM1 (0.56) | OPRM1OPRD1OPRK1OPRL1TSHR | |
| SCHEMBL9247567 | 0.73 | OPRM1 (0.49) | OPRM1OPRD1OPRK1OPRL1MC4R | |
| SCHEMBL9253066 | 0.73 | KDM4E (0.49) | OPRM1OPRD1OPRK1OPRL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5470851-A | Antihistamine, anticoagulants | SANKYO COMPANY, LIMITED (JP) | 1995-11-28 | — | — | US | claimed |
| EP-0463873-A1 | Thiazolidinecarboxylic acid amide derivatives having anti-allergic activity, their preparation and their use | Sankyo Company Limited (JP) | 1992-01-02 | — | — | EP | claimed |
| US-5470851-A | Antihistamine, anticoagulants | SANKYO COMPANY, LIMITED (JP) | 1995-11-28 | — | — | US | disclosed |
| EP-0463873-A1 | Thiazolidinecarboxylic acid amide derivatives having anti-allergic activity, their preparation and their use | Sankyo Company Limited (JP) | 1992-01-02 | — | — | EP | disclosed |