Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9100023 | 0.86 | ALOX5 (0.45) | ALOX5 | |
| SCHEMBL9216511 | 0.79 | ALDH1A1 (0.47) | ALOX5 | |
| SCHEMBL8698139 | 0.77 | ALOX5 (0.51) | ALOX5 | |
| SCHEMBL9586137 | 0.77 | ALOX5 (0.43) | ALOX5 | |
| SCHEMBL8694243 | 0.76 | ALOX5 (0.36) | ALOX5PTGS1 | |
| SCHEMBL8630367 | 0.76 | ALOX5 (0.43) | ALOX5 | |
| SCHEMBL9585927 | 0.75 | ERN1 (0.45) | ALOX5 | |
| SCHEMBL1599480 | 0.75 | ALOX5 (0.54) | ALOX5 | |
| SCHEMBL1598547 | 0.74 | ALOX5 (0.51) | ALOX5PTGS1 | |
| SCHEMBL9229297 | 0.74 | ALOX5 (0.45) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828736-A1 | SUBSTITUTED SULFONYLPHENYLHETEROCYCLES AS CYCLOOXYGENASE-2 AND 5-LIPOXYGENASE INHIBITORS | G.D. SEARLE & CO. (US) | 1998-03-18 | — | — | EP | disclosed |
| WO-1996038442-A1 | SUBSTITUTED SULFONYLPHENYLHETEROCYCLES AS CYCLOOXYGENASE-2 AND 5-LIPOXYGENASE INHIBITORS | G.D. SEARLE & CO. (US) | 1996-12-05 | — | — | WO | disclosed |