Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.57 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.52 |
| ▸ | NQO2 | P16083 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9253312 | 1.00 | ESR1 (0.57) | ESR1ESR2PTGS1PTGS2NQO2 | |
| SCHEMBL11203024 | 0.88 | MAPT (0.47) | ESR1ESR2MEN1KMT2AKDM4E | |
| SCHEMBL30495367 | 0.88 | MAPT (0.47) | ESR1ESR2MEN1KMT2AKDM4E | |
| SCHEMBL10973737 | 0.88 | MAPT (0.47) | ESR1ESR2MEN1KMT2AKDM4E | |
| SCHEMBL1128117 | 0.85 | NPC1 (0.47) | ESR1ESR2PTGS1PTGS2NQO2 | |
| SCHEMBL7026918 | 0.76 | RAB9A (0.51) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL9261761 | 0.76 | RAB9A (0.51) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL8712456 | 0.76 | ESR1 (0.80) | ESR1ESR2PTGS1PTGS2NQO2 | |
| SCHEMBL8712455 | 0.76 | ESR1 (0.80) | ESR1ESR2PTGS1PTGS2NQO2 | |
| SCHEMBL7059289 | 0.76 | ALDH1A1 (0.41) | ESR1ESR2MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5382693-A | Curing agents for epoxy resins | THE DOW CHEMICAL COMPANY (US) | 1995-01-17 | — | — | US | disclosed |
| WO-1994026690-A1 | BIS(AMINOPHENOXY)-ALPHA-SUBSTITUTED STILBENES, CURABLE MIXTURES WITH EPOXY RESINS AND CURED PRODUCTS | THE DOW CHEMICAL COMPANY (US) | 1994-11-24 | — | — | WO | disclosed |
| US-5300594-A | Bis(aminophenoxy)-alpha-substituted stilbenes, curable mixtures with epoxy resins and cured products | THE DOW CHEMICAL COMPANY (US) | 1994-04-05 | — | — | US | disclosed |