Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.39 |
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PHGDH | O43175 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7163453 | 0.90 | KMT2A (0.59) | MEN1KMT2ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL9253331 | 0.79 | SMN1; SMN2 (0.41) | MEN1KMT2APKMSMN1; SMN2FKBP1A | |
| SCHEMBL9264405 | 0.79 | SMN1; SMN2 (0.41) | MEN1KMT2APKMSMN1; SMN2FKBP1A | |
| SCHEMBL9261579 | 0.78 | MEN1 (0.45) | MEN1KMT2ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL9260421 | 0.78 | CHRM1 (0.43) | MEN1KMT2A | |
| SCHEMBL9260959 | 0.77 | KMT2A (0.42) | MEN1KMT2APKMSMN1; SMN2DPP4 | |
| SCHEMBL9262369 | 0.76 | KMT2A (0.41) | MEN1KMT2A | |
| SCHEMBL9260110 | 0.74 | STS (0.42) | MEN1KMT2APKMKDM4EALDH1A1 | |
| SCHEMBL9256844 | 0.74 | HTT (0.46) | MEN1KMT2AALDH1A1 | |
| SCHEMBL7163448 | 0.70 | SMN1; SMN2 (0.48) | MEN1KMT2ASMN1; SMN2FKBP1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5393875-A | Hypotensive, cardiotonic and antiischemic agents | HOFFMANN-LA ROCHE INC. (US) | 1995-02-28 | — | — | US | disclosed |