Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.39 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9260421 | 0.87 | CHRM1 (0.43) | KMT2AMEN1MAPTGABBR2GABBR1 | |
| SCHEMBL7163453 | 0.86 | KMT2A (0.59) | KMT2AMEN1MAPTGABBR2GABBR1 | |
| SCHEMBL9256844 | 0.84 | HTT (0.46) | KMT2AMEN1MAPTGABBR2GABBR1 | |
| SCHEMBL9260958 | 0.77 | CYP1A2 (0.42) | DPP4 | |
| SCHEMBL9253341 | 0.77 | MEN1 (0.47) | KMT2AMEN1DPP4KDM4EALDH1A1 | |
| SCHEMBL9261597 | 0.76 | GABBR2 (0.51) | KMT2AMEN1MAPTGABBR2GABBR1 | |
| SCHEMBL7655013 | 0.76 | MAPT (0.55) | KMT2AMEN1MAPTGABBR2GABBR1 | |
| SCHEMBL9261579 | 0.75 | MEN1 (0.45) | KMT2AMEN1KDM4EALDH1A1RAB9A | |
| SCHEMBL9258866 | 0.72 | HTT (0.39) | KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9257535 | 0.72 | MAPT (0.46) | KMT2AMAPTGABBR2GABBR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5393875-A | Hypotensive, cardiotonic and antiischemic agents | HOFFMANN-LA ROCHE INC. (US) | 1995-02-28 | — | — | US | disclosed |