Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9264405 | 1.00 | SMN1; SMN2 (0.41) | SMN1; SMN2KMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL8670521 | 0.90 | SMN1; SMN2 (0.48) | SMN1; SMN2KMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL7163448 | 0.90 | SMN1; SMN2 (0.48) | SMN1; SMN2KMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL9256375 | 0.80 | SMN1; SMN2 (0.42) | SMN1; SMN2KMT2AALDH1A1TSHR | |
| SCHEMBL7282676 | 0.80 | SMN1; SMN2 (0.42) | SMN1; SMN2KMT2AALDH1A1TSHR | |
| SCHEMBL9258062 | 0.80 | SMN1; SMN2 (0.42) | SMN1; SMN2KMT2AALDH1A1TSHR | |
| SCHEMBL9262743 | 0.80 | MMP8 (0.44) | SMN1; SMN2KMT2AMEN1ALDH1A1MMP8 | |
| SCHEMBL9261571 | 0.79 | SMN1; SMN2 (0.44) | SMN1; SMN2KMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL9285930 | 0.79 | MMP8 (0.43) | SMN1; SMN2KMT2AMEN1ALDH1A1MMP8 | |
| SCHEMBL9253341 | 0.79 | MEN1 (0.47) | SMN1; SMN2KMT2AMEN1ALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5393875-A | Hypotensive, cardiotonic and antiischemic agents | HOFFMANN-LA ROCHE INC. (US) | 1995-02-28 | — | — | US | disclosed |