Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.52 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 4/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1338556 | 0.90 | CYP11B1 (0.60) | CYP11B1CYP11B2MEN1KMT2ARAB9A | |
| SCHEMBL9238331 | 0.88 | MLYCD (0.53) | CYP11B1CYP11B2MEN1KMT2ARAB9A | |
| SCHEMBL9267010 | 0.88 | RAB9A (0.62) | CYP11B1CYP11B2EPHX2MEN1KMT2A | |
| SCHEMBL9264988 | 0.86 | EPHX2 (0.49) | CYP11B1CYP11B2EPHX2MEN1KMT2A | |
| SCHEMBL3628694 | 0.85 | CYP11B1 (0.56) | CYP11B1CYP11B2MEN1KMT2APOLB | |
| Hydrochloric Acid SCHEMBL3628690 | 0.84 | CYP11B1 (0.55) | CYP11B1CYP11B2MEN1KMT2APOLB | |
| SCHEMBL9271016 | 0.82 | MEN1 (0.50) | CYP11B1CYP11B2EPHX2MEN1KMT2A | |
| SCHEMBL9256110 | 0.81 | KMT2A (0.63) | MAOAMAOBMEN1KMT2ACYP1A2 | |
| SCHEMBL1337450 | 0.81 | CYP11B1 (0.54) | CYP11B1CYP11B2EPHX2POLBMAPT | |
| Phenyl Propionic Acid SCHEMBL7330085 | 0.81 | FFAR1 (0.56) | CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463071-A | Tetrazole derivatives; useful for inhibiting undesirable cell aggregation | DR. KARL THOMAE GMBH (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |