Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7589587 | 0.92 | TSHR (0.48) | TSHRALDH1A1TP53TRPA1CALM1 | |
| SCHEMBL7593691 | 0.76 | TSHR (0.48) | TSHRALDH1A1TP53TRPA1CALM1 | |
| SCHEMBL7593388 | 0.76 | TSHR (0.48) | TSHRALDH1A1TP53TRPA1CALM1 | |
| SCHEMBL618229 | 0.69 | CALM1 (0.50) | TSHRALDH1A1TP53TRPA1CALM1 | |
| SCHEMBL15349439 | 0.65 | CALM1 (0.45) | TSHRALDH1A1TP53TRPA1CALM1 | |
| SCHEMBL726277 | 0.65 | CALM1 (0.45) | TSHRALDH1A1TP53TRPA1CALM1 | |
| SCHEMBL7595495 | 0.65 | ALDH1A1 (0.46) | TSHRALDH1A1TP53TRPA1CALM1 | |
| SCHEMBL7596375 | 0.65 | ALDH1A1 (0.46) | TSHRALDH1A1TP53TRPA1CALM1 | |
| SCHEMBL8599352 | 0.65 | CES2 (0.48) | TSHRALDH1A1TP53TRPA1CALM1 | |
| SCHEMBL5615038 | 0.65 | CALM1 (0.45) | TSHRALDH1A1TP53TRPA1CALM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5387567-A | An additional polymerization catalysts consisting of a metal compounds selected from zirconium, titanium, hafnium and organosilane compound; molecular weight controller for broad molecular weight distribution | NIPPON OIL CO., LTD. (JP) | 1995-02-07 | — | — | US | disclosed |