SCHEMBL9253630

SCHEMBL9253630

C=C(C(=O)O)n1c(=O)[nH]c(=O)[nH]c1=O

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
JAK2 O60674 1/20 0.33
THRB P10828 1/20 0.33
LMNA P02545 2/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17849940 0.78 JAK2 (0.32) JAK2THRB
SCHEMBL27889745 0.75 JAK2 (0.38) JAK2THRBLMNAALDH1A1
SCHEMBL28705743 0.71 TYMP (0.39)
SCHEMBL28309445 0.71 ALDH1A1 (0.38) LMNAALDH1A1
SCHEMBL1733536 0.71 TYMP (0.35)
SCHEMBL27792808 0.70 TSHR (0.32)
SCHEMBL27843294 0.69
SCHEMBL252499 0.69 JAK2 (0.32) JAK2THRB
SCHEMBL21176776 0.68 APEX1 (0.37)
SCHEMBL5824335 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0227394-B1 COATED ABRASIVE SUITABLE FOR USE AS A LAPPING MATERIAL MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-05-02 EP claimed
EP-0388979-B1 Derivative compound of 1,3- or 1,4-bis(hexafluoroisopropyl) benzene, or 2,2-bisphenylhexafluoropropane, ink-repellent agent containing such derivative compound, head for ink jet recording treated with such ink-repellent agent and ink jet recording device equipped with such head CANON KK (JP) 1995-06-14 EP disclosed
US-5043747-A Thin layer of fluorine-containing acrylic or epoxide polymer CANON KABUSHIKI KAISHA (JP) 1991-08-27 US disclosed
EP-0388979-A2 Derivative compound of 1,3- or 1,4-bis(hexafluoroisopropyl) benzene, or 2,2-bisphenylhexafluoropropane, ink-repellent agent containing such derivative compound, head for ink jet recording treated with such ink-repellent agent and ink jet recording device equipped with such head CANON KABUSHIKI KAISHA (JP) 1990-09-26 EP disclosed