⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9253724 | 0.71 | — | — | |
| SCHEMBL9604093 | 0.70 | POLB (0.37) | — | |
| SCHEMBL9254390 | 0.63 | POLB (0.34) | — | |
| SCHEMBL3209012 | 0.60 | — | — | |
| SCHEMBL9257302 | 0.55 | CA12 (0.32) | — | |
| SCHEMBL12693215 | 0.54 | L3MBTL1 (0.31) | — | |
| SCHEMBL11967317 | 0.53 | — | — | |
| SCHEMBL3559160 | 0.52 | MAPT (0.50) | — | |
| SCHEMBL1168222 | 0.49 | ALDH1A1 (0.42) | — | |
| SCHEMBL24968744 | 0.49 | LMNA (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0434982-B1 | 5-(Amino)-triazolylcarbothioamide derivatives, process for their preparation and medicines containing them, as well as use of the former | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 1995-03-15 | — | — | EP | disclosed |
| US-5175163-A | Tranquilizer, antidepresant, antispasmodic, analgesic and antiinflammatory agent | EGIS GYOGYSZERGYAR (HU) | 1992-12-29 | — | — | US | disclosed |
| EP-0434982-A2 | 5-(Amino)-triazolylcarbothioamide derivatives, process for their preparation and medicines containing them, as well as use of the former | EGIS GYOGYSZERGYAR (HU) | 1991-07-03 | — | — | EP | disclosed |