Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 11/20 | 0.54 |
| ▸ | OPRD1 | P41143 | 10/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 10/20 | 0.54 |
| ▸ | OPRL1 | P41146 | 10/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 4/20 | 0.39 |
| ▸ | MC4R | P32245 | 1/20 | 0.38 |
| ▸ | HRH2 | P25021 | 1/20 | 0.37 |
| ▸ | GPR183 | P32249 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9247567 | 0.93 | OPRM1 (0.49) | OPRM1OPRD1OPRK1OPRL1ESR1 | |
| SCHEMBL9252838 | 0.90 | OPRM1 (0.59) | OPRM1OPRD1OPRK1OPRL1CNR1 | |
| SCHEMBL9257134 | 0.85 | OPRM1 (0.54) | OPRM1OPRD1OPRK1OPRL1CNR1 | |
| SCHEMBL8050827 | 0.79 | OPRM1 (0.58) | OPRM1OPRD1OPRK1OPRL1CNR1 | |
| SCHEMBL9257361 | 0.79 | OPRM1 (0.56) | OPRM1OPRD1OPRK1OPRL1MC4R | |
| SCHEMBL9253403 | 0.78 | OPRL1 (0.54) | OPRM1OPRD1OPRK1OPRL1CNR1 | |
| SCHEMBL8963664 | 0.78 | MEN1 (0.56) | OPRM1OPRD1OPRK1OPRL1SLC6A2 | |
| SCHEMBL9253761 | 0.78 | OPRM1 (0.54) | OPRM1OPRD1OPRK1OPRL1MC4R | |
| SCHEMBL9253066 | 0.73 | KDM4E (0.49) | OPRM1OPRD1OPRK1OPRL1CNR1 | |
| SCHEMBL9250409 | 0.73 | OPRM1 (0.49) | OPRM1OPRD1OPRK1OPRL1MC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5470851-A | Antihistamine, anticoagulants | SANKYO COMPANY, LIMITED (JP) | 1995-11-28 | — | — | US | disclosed |
| EP-0463873-A1 | Thiazolidinecarboxylic acid amide derivatives having anti-allergic activity, their preparation and their use | Sankyo Company Limited (JP) | 1992-01-02 | — | — | EP | disclosed |