Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBE2T | Q9NPD8 | 1/20 | 0.43 |
| ▸ | TMPRSS15 | P98073 | 6/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9250984 | 0.89 | UBE2T (0.46) | UBE2TTMPRSS15NPC1RAB9AALDH1A1 | |
| SCHEMBL9251456 | 0.87 | ITGB3 (0.42) | TMPRSS15GPR119ITGB3ITGA2B | |
| SCHEMBL9248315 | 0.78 | UBE2T (0.44) | UBE2TTMPRSS15NPC1RAB9AALDH1A1 | |
| SCHEMBL9253831 | 0.76 | UBE2T (0.40) | UBE2TTMPRSS15NPC1RAB9AALDH1A1 | |
| SCHEMBL9248091 | 0.76 | ITGB3 (0.56) | ITGB3ITGA2B | |
| SCHEMBL9253885 | 0.74 | UBE2T (0.44) | UBE2TTMPRSS15NPC1RAB9AALDH1A1 | |
| Hydrochloric Acid SCHEMBL9169455 | 0.73 | TMPRSS15 (0.56) | UBE2TTMPRSS15ALDH1A1HPGDITGB3 | |
| SCHEMBL9250619 | 0.72 | ITGB3 (0.47) | TMPRSS15ITGB3ITGA2B | |
| SCHEMBL9253913 | 0.71 | PRMT1 (0.53) | ALDH1A1TSHRHPGDLMNAMAPT | |
| Hydrochloric Acid SCHEMBL9173848 | 0.70 | UBE2T (0.47) | UBE2TTMPRSS15HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463071-A | Tetrazole derivatives; useful for inhibiting undesirable cell aggregation | DR. KARL THOMAE GMBH (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |