Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4686439 | 0.93 | MAPK1 (0.48) | MAPK1KDM4EHSD17B10PKMATM | |
| SCHEMBL9257344 | 0.83 | KDM4E (0.42) | MAPK1KDM4EHSD17B10PKMATM | |
| SCHEMBL28628793 | 0.81 | TSHR (0.53) | KDM4ETSHRLMNA | |
| SCHEMBL29703417 | 0.81 | TSHR (0.53) | KDM4ETSHRLMNA | |
| SCHEMBL8805901 | 0.80 | ALDH1A1 (0.44) | HSD17B10ATMLMNAALDH1A1HPGD | |
| SCHEMBL12480437 | 0.80 | MAPK1 (0.51) | MAPK1KDM4EHSD17B10PKMATM | |
| SCHEMBL21996618 | 0.78 | MAPK1 (0.50) | MAPK1KDM4EHSD17B10PKMATM | |
| SCHEMBL1060382 | 0.77 | MAPK1 (0.56) | MAPK1KDM4EHSD17B10CA12CA1 | |
| SCHEMBL2229077 | 0.76 | LMNA (0.45) | HSD17B10ATMTSHRLMNAALDH1A1 | |
| SCHEMBL7819539 | 0.76 | MAPK1 (0.52) | MAPK1KDM4EHSD17B10PKMATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5474996-A | Angiotension II inhibitors | ROUSSEL UCLAF (FR) | 1995-12-12 | — | — | US | disclosed |