Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9253828 | 0.83 | MAPK1 (0.44) | KDM4EMAPK1CA12CA1CA2 | |
| SCHEMBL9249723 | 0.82 | ALDH1A1 (0.45) | KDM4EMAPK1TSHRL3MBTL1HSD17B10 | |
| SCHEMBL8805944 | 0.81 | ALDH1A1 (0.43) | HSD17B10LMNAALDH1A1HPGD | |
| SCHEMBL5844147 | 0.80 | MAPK1 (0.46) | KDM4EMAPK1CA12CA1CA2 | |
| SCHEMBL1748473 | 0.80 | MAPK1 (0.46) | KDM4EMAPK1CA12CA1CA2 | |
| SCHEMBL9254231 | 0.80 | AGTR1 (0.44) | L3MBTL1RAB9APKM | |
| SCHEMBL4686439 | 0.79 | MAPK1 (0.48) | KDM4EMAPK1TSHRTDP1L3MBTL1 | |
| SCHEMBL1055154 | 0.79 | MAPK1 (0.53) | KDM4EMAPK1CA12CA1CA2 | |
| SCHEMBL9250317 | 0.78 | DHFR (0.40) | KDM4ERAB9AALDH1A1MAPT | |
| SCHEMBL9250685 | 0.76 | SMO (0.34) | L3MBTL1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5474996-A | Angiotension II inhibitors | ROUSSEL UCLAF (FR) | 1995-12-12 | — | — | US | disclosed |