Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.70 |
| ▸ | BCHE | P06276 | 2/20 | 0.70 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.62 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.58 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.58 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.58 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9253116 | 0.96 | ACHE (0.71) | ACHEBCHECHRM4SLC6A12TMEM97 | |
| SCHEMBL9250309 | 0.92 | ACHE (0.83) | ACHEBCHECHRM4 | |
| Fumaric Acid SCHEMBL9252669 | 0.91 | ACHE (0.64) | ACHEBCHECHRM4 | |
| Fumaric Acid SCHEMBL9252661 | 0.91 | ACHE (0.64) | ACHEBCHECHRM4 | |
| SCHEMBL9253392 | 0.85 | ACHE (0.65) | ACHEBCHECHRM4 | |
| SCHEMBL9253037 | 0.85 | ACHE (0.65) | ACHEBCHE | |
| Hydrochloric Acid SCHEMBL10474726 | 0.84 | CHRM4 (0.66) | ACHEBCHECHRM4SLC6A12TMEM97 | |
| SCHEMBL9051860 | 0.84 | DRD2 (0.67) | — | |
| SCHEMBL7381004 | 0.84 | DRD2 (0.67) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL7236442 | 0.84 | ACHE (0.66) | ACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5441967-A | Treating cerebral edema; anticholinesterase or brain function-improving agent | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-08-15 | — | — | US | disclosed |
| CN-1024548-C | Cyclic amine compounds and their use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1994-05-18 | — | — | CN | disclosed |
| US-5294625-A | 1-benzyl,4-((4-dialkylaminophenyl)carbonyl)piperidines | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-03-15 | — | — | US | disclosed |
| EP-0378207-B1 | CYCLIC AMINE COMPOUNDS AND THEIR USE | Takeda Chemical Industries, Ltd. (JP) | 1993-09-22 | — | — | EP | disclosed |
| US-5177087-A | Cerebral edema, cholinesterase inhibitor | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-01-05 | — | — | US | disclosed |
| CN-1053231-A | Cyclic amine compound and uses thereof | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1991-07-24 | — | — | CN | disclosed |
| EP-0378207-A1 | Cyclic amine compounds and their use | Takeda Chemical Industries, Ltd. (JP) | 1990-07-18 | — | — | EP | disclosed |