Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 2/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.36 |
| ▸ | TNKS | O95271 | 1/20 | 0.36 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | DHPS | P49366 | 1/20 | 0.33 |
| ▸ | PTGIR | P43119 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17276250 | 0.83 | DDB1 (0.55) | DDB1CRBNHTR1AHTR3ADAO | |
| SCHEMBL9257239 | 0.80 | CRBN (0.51) | CREBBPBRD4DDB1CRBNALDH1A1 | |
| SCHEMBL17276659 | 0.80 | MEN1 (0.37) | DDB1CRBNALDH1A1KMT2ANPC1 | |
| SCHEMBL9256649 | 0.77 | CRBN (0.51) | CREBBPDDB1CRBNTP53MAPK1 | |
| SCHEMBL8442975 | 0.76 | CRBN (0.55) | CREBBPBRD4DDB1CRBNKMT2A | |
| SCHEMBL8439360 | 0.76 | CRBN (0.47) | CREBBPBRD4DDB1CRBNALDH1A1 | |
| SCHEMBL11036165 | 0.76 | CRBN (0.47) | CREBBPBRD4DDB1CRBNALDH1A1 | |
| SCHEMBL8522217 | 0.76 | CRBN (0.47) | CREBBPBRD4DDB1CRBNALDH1A1 | |
| SCHEMBL12326005 | 0.73 | TNKS2 (0.46) | CREBBPBRD4DDB1CRBNTNKS2 | |
| SCHEMBL17276597 | 0.71 | CRBN (0.46) | CRBNALDH1A1KMT2ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995002579-A1 | SUBSTITUTED AZETIDINONE AMIDE DERIVATIVES AS ANTI-INFLAMMATORY AND ANTIDEGENERATIVE AGENTS | ZENECA LIMITED (GB) | 1995-01-26 | — | — | WO | disclosed |