Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 10/20 | 0.51 |
| ▸ | DDB1 | Q16531 | 9/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 3/20 | 0.37 |
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17276659 | 0.85 | MEN1 (0.37) | CRBNDDB1ALDH1A1MAPTGAA | |
| SCHEMBL9256649 | 0.81 | CRBN (0.51) | CRBNDDB1GAACREBBPTDP1 | |
| SCHEMBL9253852 | 0.80 | CREBBP (0.44) | CRBNDDB1ALDH1A1MAPTCREBBP | |
| SCHEMBL8442975 | 0.80 | CRBN (0.55) | CRBNDDB1MAPTGAACREBBP | |
| SCHEMBL8439360 | 0.80 | CRBN (0.47) | CRBNDDB1ALDH1A1MAPTGAA | |
| SCHEMBL11036165 | 0.80 | CRBN (0.47) | CRBNDDB1ALDH1A1MAPTGAA | |
| SCHEMBL8522217 | 0.80 | CRBN (0.47) | CRBNDDB1ALDH1A1MAPTGAA | |
| SCHEMBL9261121 | 0.79 | DDB1 (0.55) | CRBNDDB1ALDH1A1MAPTCREBBP | |
| SCHEMBL17276250 | 0.77 | DDB1 (0.55) | CRBNDDB1 | |
| SCHEMBL17276597 | 0.75 | CRBN (0.46) | CRBNALDH1A1MAPTGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995002579-A1 | SUBSTITUTED AZETIDINONE AMIDE DERIVATIVES AS ANTI-INFLAMMATORY AND ANTIDEGENERATIVE AGENTS | ZENECA LIMITED (GB) | 1995-01-26 | — | — | WO | disclosed |
| EP-0003415-A2 | Beta-Lactam compounds, processes for their preparation,compositions containing them and intermediates of use in their preparation | GLAXO GROUP LIMITED (GB) | 1979-08-08 | — | — | EP | disclosed |
| EP-0000636-A1 | Penem compounds, processes for their preparation, their use in pharmaceutical compositions and azetidinones used in their preparation | GLAXO GROUP LIMITED (GB) | 1979-02-07 | — | — | EP | disclosed |