Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 5/20 | 0.41 |
| ▸ | MMP9 | P14780 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9251339 | 0.83 | HPGD (0.49) | HPGDTSHRHSD17B10MAPTTP53 | |
| Hydrochloric Acid SCHEMBL9254302 | 0.82 | HPGD (0.48) | HPGDTSHRHSD17B10MAPTTP53 | |
| SCHEMBL3628694 | 0.80 | CYP11B1 (0.56) | HPGDTSHRHSD17B10CYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL3628690 | 0.79 | CYP11B1 (0.55) | HPGDTSHRHSD17B10CYP11B1CYP11B2 | |
| SCHEMBL1338556 | 0.79 | CYP11B1 (0.60) | CYP11B1CYP11B2MAPTPOLBALDH1A1 | |
| SCHEMBL10664707 | 0.79 | CHRNB2 (0.69) | CHRNB2CHRNA5CHRNA4MAPTAOC3 | |
| SCHEMBL9256828 | 0.78 | TSHR (0.68) | HPGDTSHRHSD17B10MAPTTP53 | |
| SCHEMBL9251061 | 0.77 | CYP11B1 (0.52) | CYP11B1CYP11B2MAPTS1PR1POLB | |
| SCHEMBL9251931 | 0.77 | CYP11B1 (0.52) | HPGDHSD17B10CYP11B1CYP11B2MAPT | |
| SCHEMBL9259632 | 0.74 | CYP11B1 (0.47) | HPGDCYP11B1CYP11B2MAPTS1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463071-A | Tetrazole derivatives; useful for inhibiting undesirable cell aggregation | DR. KARL THOMAE GMBH (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |