Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 10/20 | 0.55 |
| ▸ | RXRB | P28702 | 8/20 | 0.55 |
| ▸ | RXRG | P48443 | 6/20 | 0.55 |
| ▸ | RARB | P10826 | 12/20 | 0.48 |
| ▸ | RARG | P13631 | 11/20 | 0.48 |
| ▸ | RARA | P10276 | 9/20 | 0.47 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.47 |
| ▸ | CYP26B1 | Q9NR63 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | CRABP2 | P29373 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9186843 | 0.84 | RARA (0.47) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL10409337 | 0.81 | RARA (0.47) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL9175151 | 0.80 | RXRA (0.74) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL9175054 | 0.80 | RXRA (0.60) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL9350492 | 0.79 | ALDH1A1 (0.61) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL9253962 | 0.77 | RXRA (0.53) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL9551753 | 0.77 | RXRA (0.57) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL29440075 | 0.77 | RXRA (0.68) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL2128581 | 0.77 | RXRA (0.68) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL29204714 | 0.77 | ALDH1A1 (0.58) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0642499-A1 | RETINOIDS AND THEIR USE IN TREATING SKIN DISEASES AND LEUKEMIA | PFIZER INC. (US) | 1995-03-15 | — | — | EP | disclosed |
| WO-1993006086-A1 | RETINOIDS AND THEIR USE IN TREATING SKIN DISEASES AND LEUKEMIA | PFIZER INC. (US) | 1993-04-01 | — | — | WO | disclosed |