Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.89 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.68 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.53 |
| ▸ | HTR3B | O95264 | 1/20 | 0.53 |
| ▸ | HTR3A | P46098 | 1/20 | 0.53 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.53 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.53 |
| ▸ | PGR | P06401 | 1/20 | 0.52 |
| ▸ | RORA | P35398 | 1/20 | 0.52 |
| ▸ | RORC | P51449 | 1/20 | 0.52 |
| ▸ | RORB | Q92753 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30197876 | 1.00 | ALDH1A1 (0.89) | ALDH1A1KDM4EMAPTHTTSMN1; SMN2 | |
| SCHEMBL9262842 | 1.00 | ALDH1A1 (0.89) | ALDH1A1KDM4EMAPTHTTSMN1; SMN2 | |
| SCHEMBL1790843 | 0.94 | ALDH1A1 (1.00) | ALDH1A1KDM4EMAPTHTTSMN1; SMN2 | |
| SCHEMBL7462175 | 0.88 | ALDH1A1 (0.83) | ALDH1A1KDM4EMAPTHTTSMN1; SMN2 | |
| SCHEMBL3291974 | 0.84 | ALDH1A1 (0.72) | ALDH1A1KDM4EMAPTHTTSMN1; SMN2 | |
| SCHEMBL9255920 | 0.83 | ALDH1A1 (0.63) | ALDH1A1KDM4EMAPTHTTSMN1; SMN2 | |
| SCHEMBL7435320 | 0.82 | ALDH1A1 (0.61) | ALDH1A1KDM4EMAPTHTTSMN1; SMN2 | |
| SCHEMBL9535544 | 0.82 | KDM4E (1.00) | ALDH1A1KDM4EMAPTHTTSMN1; SMN2 | |
| SCHEMBL7437593 | 0.81 | ALDH1A1 (0.63) | ALDH1A1KDM4EMAPTHTTSMN1; SMN2 | |
| SCHEMBL11828707 | 0.80 | ALDH1A1 (0.70) | ALDH1A1KDM4EMAPTSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5382572-A | Viricides | SCHERING CORPORATION (US) | 1995-01-17 | — | — | US | disclosed |
| US-5378694-A | Herpes viricide, hypotensive agent | SCHERING CORPORATION (US) | 1995-01-03 | — | — | US | disclosed |
| EP-0550464-A1 | ANTIVIRAL COMPOUNDS AND ANTIHYPERTENSIVE COMPOUNDS | SCHERING CORPORATION (US) | 1993-07-14 | — | — | EP | disclosed |
| EP-0547145-A1 | ANTIVIRAL 2(1H)-QUINOLINONE COMPOUNDS | SCHERING CORPORATION (US) | 1993-06-23 | — | — | EP | disclosed |
| US-5190956-A | Certain N-substituted 3-oximino-2,4-dioxoquinolin-2,4-(1H)diones useful for treating viral infections | SCHERING CORPORATION (US) | 1993-03-02 | — | — | US | disclosed |
| US-5179093-A | Viricides | SCHERING CORPORATION (US) | 1993-01-12 | — | — | US | disclosed |
| US-5179107-A | Herpes | SCHERING CORPORATION (US) | 1993-01-12 | — | — | US | disclosed |
| WO-1992004328-A1 | ANTIVIRAL COMPOUNDS AND ANTIHYPERTENSIVE COMPOUNDS | SCHERING CORPORATION (US) | 1992-03-19 | — | — | WO | disclosed |
| WO-1992004326-A1 | ANTIVIRAL COMPOUNDS | SCHERING CORPORATION (US) | 1992-03-19 | — | — | WO | disclosed |