Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4897278 | 0.87 | TDP1 (0.50) | TDP1AKR1B1ALDH1A1LMNAEGFR | |
| SCHEMBL20857379 | 0.84 | TDP1 (0.58) | TDP1AKR1B1ALDH1A1LMNAEGFR | |
| SCHEMBL7312913 | 0.79 | BLM (0.49) | ALDH1A1TSHRSLC6A2CYP2D6CYP2C9 | |
| SCHEMBL313991 | 0.79 | BLM (0.49) | ALDH1A1TSHRSLC6A2CYP2D6CYP2C9 | |
| SCHEMBL1548979 | 0.77 | ALDH1A1 (0.67) | TDP1AKR1B1ALDH1A1LMNAEGFR | |
| SCHEMBL18717240 | 0.76 | TDP1 (0.59) | TDP1AKR1B1ALDH1A1LMNAEGFR | |
| SCHEMBL1655944 | 0.76 | TDP1 (0.73) | TDP1AKR1B1ALDH1A1LMNAEGFR | |
| SCHEMBL3626627 | 0.76 | SLC6A2 (0.61) | TDP1ALDH1A1LMNASLC6A2SLC6A3 | |
| SCHEMBL28746418 | 0.75 | ALDH1A1 (0.59) | TDP1ALDH1A1LMNAL3MBTL1CYP3A4 | |
| SCHEMBL10708897 | 0.75 | ALDH1A1 (0.73) | TDP1AKR1B1ALDH1A1LMNAEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5429940-A | CULTURING MICROORGANISMS TO PRODUCE PYRROLOQUINOLINEQUINONE, ADDING AN AMINO ACID OR METHYLAMINE IN THE PRESENCE OF OXYGEN TO PRODUCE OXAZOPYRROLOQUINOLINE AND RECOVERING PRODUCT | MITSUBISHI GAS CHEMICAL COMPANY (JP) | 1995-07-04 | — | — | US | disclosed |
| US-5236930-A | Aldose reductase inhibitors | MITBUSHI GAS CHEMICAL COMPANY, INC. (JP) | 1993-08-17 | — | — | US | disclosed |