Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | HTR1D | P28221 | 1/20 | 0.48 |
| ▸ | HTR1B | P28222 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA7 | P43166 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL313991 | 1.00 | BLM (0.49) | BLMNPSR1CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL5796163 | 0.83 | HSD17B10 (0.55) | BLMNPSR1CYP2C9HTR1AHTR2A | |
| SCHEMBL5796160 | 0.83 | HSD17B10 (0.55) | BLMNPSR1CYP2C9HTR1AHTR2A | |
| SCHEMBL10706064 | 0.83 | HTR2A (0.56) | HTR1AHTR2AHTR2CHTR2BTAAR1 | |
| SCHEMBL5066588 | 0.81 | AKR1C3 (0.44) | — | |
| SCHEMBL4328756 | 0.80 | CA12 (0.43) | CYP2C9CA12CA1CA2CA7 | |
| SCHEMBL9254045 | 0.79 | TDP1 (0.50) | CYP2D6CYP2C9CYP2C19SLC6A2ALDH1A1 | |
| SCHEMBL1995440 | 0.78 | CA12 (0.57) | CA12CA1CA2CA7CA9 | |
| SCHEMBL11141533 | 0.77 | FOLH1 (0.50) | CYP2D6CYP2C9CYP2C19CA12CA1 | |
| SCHEMBL264745 | 0.77 | FOLH1 (0.50) | CYP2D6CYP2C9CYP2C19CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4772586-A | ANTAGONISTS OF ANTIDIURETIC AND VASOPRESSOR ACTIVITY OF HORMONE | MEDICAL COLLEGE OF OHIO (US) | 1988-09-20 | — | — | US | claimed |
| EP-0273645-A2 | Novel derivatives of arginine vasopressin antagonists | THE MEDICAL COLLEGE OF OHIO (US) | 1988-07-06 | — | — | EP | claimed |
| US-4772586-A | ANTAGONISTS OF ANTIDIURETIC AND VASOPRESSOR ACTIVITY OF HORMONE | MEDICAL COLLEGE OF OHIO (US) | 1988-09-20 | — | — | US | disclosed |
| EP-0273645-A2 | Novel derivatives of arginine vasopressin antagonists | THE MEDICAL COLLEGE OF OHIO (US) | 1988-07-06 | — | — | EP | disclosed |
| US-4714696-A | Novel derivatives of arginine vasopressin antagonists | MEDICAL COLLEGE OF OHIO (US) | 1987-12-22 | — | — | US | disclosed |
| US-4649130-A | Novel derivatives of arginine vasopressin antagonists | MEDICAL COLLEGE OF OHIO (US) | 1987-03-10 | — | — | US | disclosed |
| EP-0189326-A2 | Derivatives of arginine vasopressin antagonists | Medical College of Ohio (US) | 1986-07-30 | — | — | EP | disclosed |
| US-4551445-A | Derivatives of arginine vasopressin antagonists | THE MEDICAL COLLEGE OF OHIO (US) | 1985-11-05 | — | — | US | disclosed |
| EP-0151016-A2 | Arginine vasopressin antagonists | Medical College of Ohio (US) | 1985-08-07 | — | — | EP | disclosed |
| EP-0061356-B1 | ANTAGONISTS OF THE ANTIDIURETIC AND/OR VASOPRESSOR ACTION OF ARGININE VASOPRESSIN | Medical College of Ohio (US) | 1985-07-17 | — | — | EP | disclosed |
| EP-0138604-A2 | Arginine vasopressin antagonists | Medical College of Ohio (US) | 1985-04-24 | — | — | EP | disclosed |
| US-4491577-A | Antagonists of the antidiuretic action of arginine vasopressin | THE MEDICAL COLLEGE OF OHIO (US) | 1985-01-01 | — | — | US | disclosed |
| EP-0115379-A2 | Antagonists of the antidiuretic action of arginine vasopressin | Medical College of Ohio (US) | 1984-08-08 | — | — | EP | disclosed |
| US-4399125-A | CYCLIC OLIGOPEPTIDES | TRUSTEES OF COLUMBIA UNIVERSITY THE, A CORP. OF NY. | 1983-08-16 | — | — | US | disclosed |
| EP-0061356-A2 | Antagonists of the antidiuretic and/or vasopressor action of arginine vasopressin | Medical College of Ohio (US) | 1982-09-29 | — | — | EP | disclosed |