Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 5/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.51 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.46 |
| ▸ | NQO2 | P16083 | 4/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | F10 | P00742 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9254388 | 0.86 | F2 (0.43) | SIRT5NQO2F2F10PRSS1 | |
| SCHEMBL1796438 | 0.83 | NPC1 (0.55) | NQO2NPC1RAB9APTGS2CASP3 | |
| Hydrochloric Acid SCHEMBL1795286 | 0.82 | TOP2A (0.56) | NQO2NPC1RAB9APTGS2CASP3 | |
| SCHEMBL9255174 | 0.81 | NQO2 (0.67) | ITGB3ITGA2BNQO2F2F10 | |
| SCHEMBL1797990 | 0.81 | NPC1 (0.67) | NQO2NPC1RAB9APTGS2CASP3 | |
| SCHEMBL1797705 | 0.81 | NPC1 (0.67) | NQO2NPC1RAB9APTGS2CASP3 | |
| Hydrochloric Acid SCHEMBL1798761 | 0.79 | NPC1 (0.65) | NQO2NPC1RAB9APTGS2CASP3 | |
| SCHEMBL7118598 | 0.79 | ITGB3 (0.74) | ITGB3ITGA2BF2F10PRSS1 | |
| SCHEMBL9250114 | 0.77 | ITGB3 (0.58) | ITGB3ITGA2BNQO2F2F10 | |
| SCHEMBL9258497 | 0.77 | NPC1 (0.53) | ITGB3ITGA2BF2PRSS1TMPRSS15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463071-A | Tetrazole derivatives; useful for inhibiting undesirable cell aggregation | DR. KARL THOMAE GMBH (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |