Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 13/20 | 0.67 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | TOP1 | P11387 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | CASP1 | P29466 | 1/20 | 0.63 |
| ▸ | CASP7 | P55210 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | TOP2A | P11388 | 1/20 | 0.61 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.61 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.59 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.59 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.53 |
| ▸ | TMPRSS15 | P98073 | 2/20 | 0.53 |
| ▸ | F2 | P00734 | 1/20 | 0.49 |
| ▸ | F10 | P00742 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7118598 | 0.86 | ITGB3 (0.74) | ITGB3ITGA2BPRSS1TMPRSS15F2 | |
| SCHEMBL9254121 | 0.84 | ALDH1A1 (0.64) | NQO2PRMT1ALDH1A1TOP1HPGD | |
| SCHEMBL9250170 | 0.84 | NQO2 (0.61) | NQO2PRMT1ALDH1A1TOP1HPGD | |
| SCHEMBL9257683 | 0.83 | ITGB3 (0.56) | NQO2ITGB3ITGA2BPRSS1TMPRSS15 | |
| SCHEMBL9254150 | 0.81 | ITGB3 (0.51) | NQO2ITGB3ITGA2BPRSS1TMPRSS15 | |
| SCHEMBL9254195 | 0.80 | NQO2 (0.61) | NQO2ITGB3ITGA2BPRSS1TMPRSS15 | |
| Furamidine SCHEMBL549198 | 0.79 | NQO2 (1.00) | NQO2PRMT1ALDH1A1TOP1HPGD | |
| SCHEMBL9250114 | 0.79 | ITGB3 (0.58) | NQO2ITGB3ITGA2BPRSS1TMPRSS15 | |
| Acetic Acid SCHEMBL3506391 | 0.78 | NQO2 (0.82) | NQO2PRMT1ALDH1A1TOP1HPGD | |
| SCHEMBL4357250 | 0.78 | NQO2 (0.96) | NQO2PRMT1ALDH1A1TOP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463071-A | Tetrazole derivatives; useful for inhibiting undesirable cell aggregation | DR. KARL THOMAE GMBH (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |