Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 13/20 | 0.57 |
| ▸ | ITGA2B | P08514 | 13/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 4/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 4/20 | 0.43 |
| ▸ | F2 | P00734 | 2/20 | 0.43 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.43 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9248696 | 0.88 | PKM (0.43) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL9248909 | 0.86 | UBE2T (0.47) | ITGB3ITGA2BHTTF10KMT2A | |
| SCHEMBL9248315 | 0.75 | UBE2T (0.44) | KMT2AMEN1NPC1ALDH1A1RAB9A | |
| SCHEMBL9248091 | 0.74 | ITGB3 (0.56) | ITGB3ITGA2BALOX15PRSS1PRSS2 | |
| SCHEMBL9258264 | 0.74 | ITGB3 (0.64) | ITGB3ITGA2BALOX15PRSS1PRSS2 | |
| SCHEMBL9253862 | 0.73 | ITGB3 (0.53) | ITGB3ITGA2BALOX15PRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL8988856 | 0.72 | ITGB3 (0.69) | ITGB3ITGA2BALOX15PRSS1F2 | |
| SCHEMBL9257912 | 0.70 | NR1H4 (0.61) | ITGB3ITGA2BPRSS1KMT2AMEN1 | |
| SCHEMBL9173941 | 0.69 | ITGB3 (0.57) | ITGB3ITGA2BALOX15PRSS1PRSS2 | |
| SCHEMBL7341889 | 0.68 | ITGB3 (0.76) | ITGB3ITGA2BALOX15PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463071-A | Tetrazole derivatives; useful for inhibiting undesirable cell aggregation | DR. KARL THOMAE GMBH (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |