Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.44 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9257683 | 0.85 | ITGB3 (0.56) | NR1H4RAB9ANPC1MAPTPRSS1 | |
| SCHEMBL9250754 | 0.85 | KMT2A (0.49) | NR1H4RAB9AKMT2ANPC1MEN1 | |
| SCHEMBL561946 | 0.80 | NR1H4 (0.69) | NR1H4RAB9AKMT2ANPC1MEN1 | |
| SCHEMBL24073125 | 0.79 | NR1H4 (0.64) | NR1H4RAB9AKMT2ANPC1MEN1 | |
| SCHEMBL9259668 | 0.78 | RXRA (0.71) | RAB9ANPC1ALDH1A1KDM4EPRSS1 | |
| SCHEMBL17384053 | 0.74 | WDR5 (0.66) | RAB9AKMT2ANPC1MEN1ALDH1A1 | |
| SCHEMBL3518708 | 0.73 | NR1H4 (0.60) | NR1H4RAB9AKMT2ANPC1MEN1 | |
| SCHEMBL9254121 | 0.73 | ALDH1A1 (0.64) | ALDH1A1KDM4EPKMMAPTPRSS1 | |
| Hydrochloric Acid SCHEMBL17377346 | 0.72 | WDR5 (0.63) | RAB9AKMT2ANPC1MEN1ALDH1A1 | |
| SCHEMBL9255174 | 0.71 | NQO2 (0.67) | ALDH1A1PRSS1TMPRSS15NQO2ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463071-A | Tetrazole derivatives; useful for inhibiting undesirable cell aggregation | DR. KARL THOMAE GMBH (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |