Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 3/20 | 0.38 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 3/20 | 0.37 |
| ▸ | TYMS | P04818 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | PLK4 | O00444 | 1/20 | 0.35 |
| ▸ | PTGIR | P43119 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11819273 | 0.81 | MAOA (0.50) | MAOAALDH1A1MAOBMAPK1GRM5 | |
| SCHEMBL31337906 | 0.80 | MAOA (0.48) | MAOAALDH1A1MAOBTYMSMAPK1 | |
| SCHEMBL3289392 | 0.80 | MAOA (0.48) | MAOAALDH1A1MAOBTYMSMAPK1 | |
| SCHEMBL29543964 | 0.80 | MAOA (0.48) | MAOAALDH1A1MAOBTYMSMAPK1 | |
| SCHEMBL17643520 | 0.79 | ALDH1A1 (0.50) | MAOAALDH1A1MAPTMAOBTYMS | |
| SCHEMBL8953701 | 0.79 | IDO1 (0.51) | ALDH1A1MAPTEGFRMTNR1AMTNR1B | |
| SCHEMBL3285262 | 0.78 | HTR2C (0.47) | MAOAALDH1A1MAPTMAOBMAPK1 | |
| SCHEMBL30385602 | 0.78 | HTR2C (0.47) | MAOAALDH1A1MAPTMAOBMAPK1 | |
| SCHEMBL6975747 | 0.78 | TSHR (0.59) | MAOAALDH1A1MAPTAPPMAOB | |
| SCHEMBL10595966 | 0.78 | MAOA (0.47) | MAOAALDH1A1MAOBTYMSMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5432194-A | Antiallergens, antinflammatory agents | ABBOTT LABORATORIES (US) | 1995-07-11 | — | — | US | disclosed |
| WO-1994026264-A1 | (4-ALKOXYPYRAN-4-YL) SUBSTITUTED ARYLALKYLARYL-, ARYLALKENYLARYL-, AND ARYLALKYNYLARYLUREA INHIBITORS OF 5-LIPOXYGENASE | ABBOTT LABORATORIES (US) | 1994-11-24 | — | — | WO | disclosed |