Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | CDC25A | P30304 | 1/20 | 0.44 |
| ▸ | CDC25B | P30305 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9128067 | 0.84 | TSHR (0.46) | MTNR1AMTNR1BKMT2AMEN1 | |
| SCHEMBL10925259 | 0.84 | MAPT (0.66) | IDO1SMN1; SMN2MAPTALDH1A1RAB9A | |
| SCHEMBL10920706 | 0.82 | NAPRT (0.67) | SMN1; SMN2MAPTALDH1A1RAB9AGAA | |
| SCHEMBL27733790 | 0.82 | ALDH1A1 (0.61) | SMN1; SMN2MAPTALDH1A1MTNR1AMTNR1B | |
| SCHEMBL3959278 | 0.82 | SMN1; SMN2 (0.64) | SMN1; SMN2MAPTALDH1A1RAB9AGAA | |
| SCHEMBL8953624 | 0.81 | MTNR1A (0.44) | SMN1; SMN2MAPTMTNR1AMTNR1BGAA | |
| SCHEMBL9048923 | 0.80 | ALDH1A1 (0.66) | SMN1; SMN2MAPTALDH1A1HTTKMT2A | |
| SCHEMBL9254481 | 0.79 | MAOA (0.40) | MAPTALDH1A1MTNR1AMTNR1BTAAR1 | |
| SCHEMBL13836493 | 0.79 | ALDH1A1 (0.61) | SMN1; SMN2MAPTALDH1A1RAB9AKMT2A | |
| SCHEMBL11642673 | 0.77 | RAB9A (0.52) | SMN1; SMN2MAPTALDH1A1MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5484786-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS | ABBOTT LABORATORIES (US) | 1996-01-16 | — | — | US | disclosed |
| US-5432194-A | Antiallergens, antinflammatory agents | ABBOTT LABORATORIES (US) | 1995-07-11 | — | — | US | disclosed |
| US-5407959-A | Antiallergens, antiinflammatory agents | ABBOTT LABORATORIES (US) | 1995-04-18 | — | — | US | disclosed |
| WO-1994026264-A1 | (4-ALKOXYPYRAN-4-YL) SUBSTITUTED ARYLALKYLARYL-, ARYLALKENYLARYL-, AND ARYLALKYNYLARYLUREA INHIBITORS OF 5-LIPOXYGENASE | ABBOTT LABORATORIES (US) | 1994-11-24 | — | — | WO | disclosed |