Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.61 |
| ▸ | NPC1 | O15118 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | MAOB | P27338 | 8/20 | 0.58 |
| ▸ | MAOA | P21397 | 3/20 | 0.58 |
| ▸ | CASP3 | P42574 | 2/20 | 0.58 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.58 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.58 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | AR | P10275 | 2/20 | 0.51 |
| ▸ | ACHE | P22303 | 7/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA5A | P35218 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9254545 | 0.88 | MAOB (0.61) | RAB9ANPC1MEN1KMT2AMAOB | |
| SCHEMBL9267165 | 0.88 | KMT2A (0.51) | RAB9ANPC1KMT2AMAOBMAOA | |
| SCHEMBL9263722 | 0.87 | NPC1 (0.58) | RAB9ANPC1MEN1KMT2AMAOB | |
| SCHEMBL9259465 | 0.86 | KMT2A (0.44) | RAB9ANPC1MEN1KMT2AMAOB | |
| SCHEMBL9258559 | 0.85 | MAOB (0.48) | RAB9ANPC1MEN1KMT2AMAOB | |
| SCHEMBL9267747 | 0.85 | MAOB (0.48) | RAB9ANPC1MEN1KMT2AMAOB | |
| SCHEMBL9160911 | 0.80 | MEN1 (0.44) | RAB9ANPC1MEN1KMT2AMAOB | |
| SCHEMBL9263552 | 0.77 | MAOB (0.47) | RAB9ANPC1MEN1KMT2AMAOB | |
| SCHEMBL9265290 | 0.77 | MAOB (0.63) | RAB9ANPC1KMT2AMAOBMAOA | |
| SCHEMBL9268118 | 0.77 | ALDH1A1 (0.48) | RAB9ANPC1MEN1KMT2AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5424320-A | Antihistamine, antiallergic, antiinflammatory and cytoprotective agents | MERCK FROSST CANADA, INC. (CA) | 1995-06-13 | — | — | US | disclosed |