Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9254559 | 1.00 | RAB9A (0.53) | RAB9AKDM4EALDH1A1TDP1HPGD | |
| SCHEMBL9253242 | 0.88 | ALOX5 (0.52) | RAB9AKDM4ENPC1SMN1; SMN2CASP3 | |
| SCHEMBL9253236 | 0.88 | ALOX5 (0.52) | RAB9AKDM4ENPC1SMN1; SMN2CASP3 | |
| SCHEMBL9090789 | 0.88 | RAB9A (0.47) | RAB9AKDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL9090792 | 0.88 | RAB9A (0.47) | RAB9AKDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL9179031 | 0.88 | KDM4E (0.48) | RAB9AKDM4EALDH1A1TDP1HPGD | |
| SCHEMBL9179028 | 0.88 | KDM4E (0.48) | RAB9AKDM4EALDH1A1TDP1HPGD | |
| SCHEMBL9262429 | 0.85 | ALOX5 (0.48) | RAB9AKDM4ENPC1SMN1; SMN2CASP3 | |
| SCHEMBL9262438 | 0.85 | ALOX5 (0.48) | RAB9AKDM4ENPC1SMN1; SMN2CASP3 | |
| SCHEMBL9258868 | 0.84 | MAPT (0.58) | RAB9AKDM4EALDH1A1TDP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5459154-A | Enzyme inhibitors as antiinflammatory agents and treatment of atherosclerosis | AMERICAN HOME PRODUCTS CORPORATION (US) | 1995-10-17 | — | — | US | disclosed |