Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.37 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.37 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 7/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9568798 | 0.82 | DAO (0.40) | ALDH1A1MAPTKDM4EKMT2APTGS2 | |
| SCHEMBL9093660 | 0.69 | PTGS2 (0.33) | PTGS2 | |
| SCHEMBL1857270 | 0.67 | PTGS2 (0.50) | LMNAALDH1A1HPGDMAPTKDM4E | |
| SCHEMBL26983495 | 0.64 | NPC1 (0.40) | LMNAALDH1A1HPGDMAPTKDM4E | |
| SCHEMBL8629996 | 0.63 | DAO (0.67) | LMNANPSR1PPARGNCOA2NCOA1 | |
| SCHEMBL70027 | 0.63 | NPSR1 (0.67) | LMNANPSR1PPARGNCOA2NCOA1 | |
| SCHEMBL20524639 | 0.62 | PTGS2 (0.51) | LMNAALDH1A1HPGDMAPTKDM4E | |
| SCHEMBL13279340 | 0.62 | PTGS2 (0.44) | LMNAALDH1A1MAPTKDM4EMAPK1 | |
| SCHEMBL21771492 | 0.61 | LMNA (0.38) | LMNAALDH1A1HPGDMAPTKDM4E | |
| SCHEMBL19555810 | 0.61 | FFAR2 (0.41) | LMNANPSR1PPARGNCOA2NCOA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5395845-A | Insecticides | ROUSSEL-UCLAF (FR) | 1995-03-07 | — | — | US | disclosed |