SCHEMBL9254751

SCHEMBL9254751

O=C(O)c1cccc(-c2c(O)c(C(=O)O)cc3ccccc23)c1O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HNF4A P41235 1/20 0.58
POLB P06746 1/20 0.55
GPR35 Q9HC97 1/20 0.55
SOS1 Q07889 1/20 0.54
CYP2D6 P10635 1/20 0.52
LDHA P00338 1/20 0.50
NR4A1 P22736 1/20 0.50
NR4A2 P43354 1/20 0.50
NR4A3 Q92570 1/20 0.50
MCL1 Q07820 1/20 0.48
ACMSD Q8TDX5 1/20 0.48
HSD17B10 Q99714 3/20 0.47
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
HPGD P15428 2/20 0.47
MAPT P10636 2/20 0.47
GRIN2D O15399 1/20 0.47
GRIN2A Q12879 1/20 0.47
GRIN2B Q13224 1/20 0.47
GRIN2C Q14957 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL989695 0.85 POLB (0.67) POLBGPR35SOS1CYP2D6LDHA
SCHEMBL11067214 0.81 POLB (0.61) POLBGPR35SOS1CYP2D6LDHA
SCHEMBL24891573 0.80 POLB (0.59) POLBGPR35SOS1CYP2D6LDHA
SCHEMBL2534284 0.79 NR4A1 (0.63) HNF4APOLBGPR35SOS1LDHA
SCHEMBL28053504 0.78 HNF4A (0.61) HNF4APOLBGPR35SOS1CYP2D6
SCHEMBL9276076 0.77 SOS1 (0.77) POLBGPR35SOS1LDHANR4A1
SCHEMBL8463472 0.77 POLB (0.56) POLBGPR35SOS1CYP2D6LDHA
SCHEMBL8057702 0.77 MEN1 (0.70) POLBGPR35SOS1CYP2D6LDHA
SCHEMBL3391301 0.77 POLB (0.69) POLBGPR35CYP2D6LDHANR4A1
SCHEMBL18585170 0.76 XDH (0.64) HNF4APOLBGPR35SOS1CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0338808-B1 Alkyl salicylate resin for carbonless copy paper and imaging use SCHENECTADY INT INC (US) 1995-08-23 EP disclosed
US-5017546-A Metallized phenolic resins SCHENECTADY INTERNATIONAL, INC. 1991-05-21 US disclosed
EP-0338808-A2 Alkyl salicylate resin for carbonless copy paper and imaging use SCHENECTADY INTERNATIONAL, INC. (US) 1989-10-25 EP disclosed