Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 5/20 | 0.36 |
| ▸ | CA1 | P00915 | 5/20 | 0.36 |
| ▸ | CA2 | P00918 | 5/20 | 0.36 |
| ▸ | CA7 | P43166 | 5/20 | 0.36 |
| ▸ | CA9 | Q16790 | 5/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9258671 | 1.00 | SMN1; SMN2 (0.38) | SMN1; SMN2ALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL9258943 | 0.83 | KDM4E (0.36) | SMN1; SMN2ALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL9259734 | 0.83 | KDM4E (0.36) | SMN1; SMN2ALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL9261637 | 0.82 | ALOX15 (0.41) | SMN1; SMN2ALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL9259471 | 0.82 | ALOX15 (0.41) | SMN1; SMN2ALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL9251348 | 0.75 | CA12 (0.49) | SMN1; SMN2ALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL8580093 | 0.75 | CA12 (0.49) | SMN1; SMN2ALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL5337504 | 0.75 | PTGS2 (0.47) | SMN1; SMN2ALDH1A1CYP1A2MEN1HPGD | |
| SCHEMBL9259996 | 0.74 | HSP90AA1 (0.41) | SMN1; SMN2ALDH1A1CYP1A2MEN1HPGD | |
| SCHEMBL9260914 | 0.73 | HSP90AA1 (0.41) | SMN1; SMN2ALDH1A1CYP1A2CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5439909-A | 2-Substituted with amide or thioamide group; antioxidant for lipoproteins, antilipemic agents, anticholesterol agents | ADIR ET COMPAGNIE (FR) | 1995-08-08 | — | — | US | disclosed |
| US-5420132-A | Antilipemic agents | ADIR ET COMPAGNIE (FR) | 1995-05-30 | — | — | US | disclosed |