Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 3/20 | 0.62 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.62 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.55 |
| ▸ | OXTR | P30559 | 1/20 | 0.55 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8558906 | 0.87 | AVPR2 (0.71) | AVPR2OXTRAVPR1A | |
| SCHEMBL3607075 | 0.76 | KCNK3 (0.81) | KCNK3KCNK9RAB9APOLBPKM | |
| SCHEMBL11668137 | 0.75 | KCNK3 (0.84) | KCNK3KCNK9RAB9APOLBPKM | |
| SCHEMBL2107301 | 0.75 | KCNK3 (0.74) | KCNK3KCNK9RAB9APOLBPKM | |
| Hydrochloric Acid SCHEMBL2107304 | 0.75 | KCNK3 (0.78) | KCNK3KCNK9RAB9APOLBPKM | |
| SCHEMBL14818771 | 0.75 | KCNK3 (0.74) | KCNK3KCNK9RAB9APOLBPKM | |
| SCHEMBL8561006 | 0.74 | AVPR2 (0.75) | AVPR2OXTRAVPR1A | |
| SCHEMBL8559901 | 0.74 | AVPR2 (0.63) | AVPR2OXTRAVPR1A | |
| SCHEMBL3592038 | 0.74 | RAB9A (0.78) | KCNK3KCNK9RAB9APOLBPKM | |
| SCHEMBL5210945 | 0.73 | HTR1F (0.67) | KCNK3KCNK9RAB9APOLBPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7179430-A | — | — | None | — | — | JP | disclosed |
| JP-H07179430-A | TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONIST | AMERICAN CYANAMID CO | 1995-07-18 | — | — | JP | disclosed |