SCHEMBL2107301

SCHEMBL2107301

Cc1ccccc1C(=O)Nc1cccc(C(=O)Cl)c1

nearest known ligand 0.74

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KCNK3 O14649 4/20 0.74
KCNK9 Q9NPC2 4/20 0.74
POLB P06746 4/20 0.67
RAB9A P51151 2/20 0.67
PKM P14618 1/20 0.67
SMN1; SMN2 Q16637 3/20 0.65
ALDH1A1 P00352 3/20 0.65
HPGD P15428 1/20 0.64
KMT2A Q03164 4/20 0.63
MEN1 O00255 2/20 0.63
TP53 P04637 1/20 0.61
THRB P10828 1/20 0.61
MAPT P10636 1/20 0.60
HTT P42858 1/20 0.60
F2R P25116 2/20 0.59
DHODH Q02127 1/20 0.57
RXFP1 Q9HBX9 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3607075 0.87 KCNK3 (0.81) KCNK3KCNK9POLBRAB9APKM
SCHEMBL11668137 0.86 KCNK3 (0.84) KCNK3KCNK9POLBRAB9APKM
Hydrochloric Acid SCHEMBL2107304 0.85 KCNK3 (0.78) KCNK3KCNK9POLBRAB9APKM
SCHEMBL14818771 0.85 KCNK3 (0.74) KCNK3KCNK9POLBRAB9APKM
SCHEMBL3592038 0.84 RAB9A (0.78) KCNK3KCNK9POLBRAB9APKM
SCHEMBL2005896 0.84 KCNK3 (0.76) KCNK3KCNK9POLBRAB9APKM
SCHEMBL5237637 0.83 HPGD (0.70) KCNK3KCNK9POLBRAB9ASMN1; SMN2
SCHEMBL2009483 0.82 SMN1; SMN2 (0.74) KCNK3KCNK9RAB9ASMN1; SMN2ALDH1A1
SCHEMBL12225785 0.82 FADS1 (0.70) KCNK3KCNK9POLBRAB9APKM
SCHEMBL533767 0.81 KCNK3 (0.81) KCNK3KCNK9POLBRAB9APKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230373947-A1 AMIDE DERIVATIVES, PROCESS FOR PREPARATION THEREOF AND USE THEREOF AS INSECTICIDE MITSUI CHEMICALS, INC. (JP) 2023-11-23 US disclosed
US-11760742-B2 Amide derivatives, process for preparation thereof and use thereof as insecticide MITSUI CHEMICALS, INC. (JP) 2023-09-19 US disclosed
US-20210230135-A1 AMIDE DERIVATIVES, PROCESS FOR PREPARATION THEREOF AND USE THEREOF AS INSECTICIDE MITSUI CHEMICALS, INC. (JP) 2021-07-29 US disclosed
US-10995081-B2 Amide derivatives, process for preparation thereof and use thereof as insecticide MITSUI CHEMICALS, INC. (JP) 2021-05-04 US disclosed
US-10435385-B2 Amide derivatives, process for preparation thereof and use thereof as insecticide MITSUI CHEMICALS, INC. (JP) 2019-10-08 US disclosed
US-20180134681-A1 AMIDE DERIVATIVES, PROCESS FOR PREPARATION THEREOF AND USE THEREOF AS INSECTICIDE MITSUI CHEMICALS, INC. (JP) 2018-05-17 US disclosed
US-9920026-B2 Amide derivatives, process for preparation thereof and use thereof as insecticide MITSUI CHEMICALS, INC. (JP) 2018-03-20 US disclosed
EP-1714958-B9 AMIDE DERIVATIVES, PROCESS FOR PRODUCTION OF THE SAME, AND METHOD FOR APPLICATION THEREOF AS INSECTICIDE MITSUI CHEMICALS AGRO INC (JP) 2017-05-31 EP disclosed
EP-1714958-B1 AMIDE DERIVATIVES, PROCESS FOR PRODUCTION OF THE SAME, AND METHOD FOR APPLICATION THEREOF AS INSECTICIDE MITSUI CHEMICALS AGRO INC (JP) 2016-12-21 EP disclosed
US-20160002198-A1 AMIDE DERIVATIVES, PROCESS FOR PREPARATION THEREOF AND USE THEREOF AS INSECTICIDE MITSUI CHEMICALS, INC. (JP) 2016-01-07 US disclosed
CN-1926094-B Amide derivatives, process for their preparation and their use as pesticides MITSUI CHEMICALS INC 2011-05-25 CN disclosed
CN-101906053-A Amide derivatives MITSUI CHEMICALS INC 2010-12-08 CN disclosed
US-20090192167-A1 Insecticidal and fungicidal composition MITSUI CHEMICALS, INC. (JP) 2009-07-30 US disclosed
US-20090162453-A1 COMPOSITION FOR PREVENTING HARMFUL ORGANISMS MITSUI CHEMICALS, INC (JP) 2009-06-25 US disclosed
CN-101367748-A Amide derivatives, process for production of the same, and method for application thereof as insecticide MITSUI CHEMICALS INC (JP) 2009-02-18 CN disclosed
EP-1938685-A1 INSECTICIDAL AND BACTERICIDAL COMPOSITION Mitsui Chemicals, Inc. (JP) 2008-07-02 EP disclosed
EP-1913815-A1 PEST CONTROL COMPOSITION Mitsui Chemicals, Inc. (JP) 2008-04-23 EP disclosed
US-20070275980-A1 Amide Derivatives, Process For Preparation Thereof And Use Thereof As Insecticide MITSUI CHEMICALS, INC. (JP) 2007-11-29 US disclosed
CN-1926094-A Amide derivatives, process for their preparation and their use as pesticides MITSUI CHEMICALS INC (JP) 2007-03-07 CN disclosed
EP-1714958-A1 AMIDE DERIVATIVES, PROCESS FOR PRODUCTION OF THE SAME, AND METHOD FOR APPLICATION THEREOF AS INSECTICIDE Mitsui Chemicals, Inc. (JP) 2006-10-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070275980-A1 Amide Derivatives, Process For Preparation Thereof And Use Thereof As Insecticide CYP1A1, CYP4B1, CYP2E1 KCNK3 1494/4885KCNK9 2801/4885POLB 2928/4885
US-20180134681-A1 AMIDE DERIVATIVES, PROCESS FOR PREPARATION THEREOF AND USE THEREOF AS INSECTICIDE CYP1A1, CYP4B1, CYP2E1 KCNK3 1494/4885KCNK9 2801/4885POLB 2928/4885
US-20160002198-A1 AMIDE DERIVATIVES, PROCESS FOR PREPARATION THEREOF AND USE THEREOF AS INSECTICIDE CYP1A1, CYP4B1, CYP2E1 KCNK3 1494/4885KCNK9 2801/4885POLB 2928/4885
US-20090192167-A1 Insecticidal and fungicidal composition NOX3, PRDX1, CYP4X1 KCNK3 673/4885KCNK9 1825/4885POLB 4499/4885
US-20230373947-A1 AMIDE DERIVATIVES, PROCESS FOR PREPARATION THEREOF AND USE THEREOF AS INSECTICIDE DDT, CYP4B1, CYP2E1 KCNK3 3042/4885KCNK9 1953/4885POLB 4176/4885
US-20210230135-A1 AMIDE DERIVATIVES, PROCESS FOR PREPARATION THEREOF AND USE THEREOF AS INSECTICIDE DDT, CYP4B1, CYP2E1 KCNK3 3042/4885KCNK9 1953/4885POLB 4176/4885
US-10435385-B2 Amide derivatives, process for preparation thereof and use thereof as insecticide DDT, CYP4B1, CYP2E1 KCNK3 3042/4885KCNK9 1953/4885POLB 4176/4885
US-20090162453-A1 COMPOSITION FOR PREVENTING HARMFUL ORGANISMS PRDX3, CYP1A1, GSTA1 KCNK3 2594/4885KCNK9 3056/4885POLB 2739/4885
US-11760742-B2 Amide derivatives, process for preparation thereof and use thereof as insecticide DDT, CYP4B1, CYP2E1 KCNK3 3042/4885KCNK9 1953/4885POLB 4176/4885
US-10995081-B2 Amide derivatives, process for preparation thereof and use thereof as insecticide DDT, CYP4B1, CYP2E1 KCNK3 3042/4885KCNK9 1953/4885POLB 4176/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.