Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.41 |
| ▸ | PDE4A | P27815 | 2/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.40 |
| ▸ | ESR1 | P03372 | 5/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.39 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6521502 | 0.77 | BACE1 (0.61) | BACE1HTTPDE4BPDE4APDE4C | |
| SCHEMBL16901963 | 0.76 | BACE1 (0.41) | BACE1HTTPDE4BPDE4APDE4C | |
| SCHEMBL21382004 | 0.76 | BACE1 (0.65) | BACE1HTTPDE4BPDE4APDE4C | |
| Methane SCHEMBL28838467 | 0.74 | BACE1 (0.62) | BACE1HTTPDE4BPDE4APDE4C | |
| Phosphine SCHEMBL1744080 | 0.74 | BACE1 (0.62) | BACE1HTTPDE4BPDE4APDE4C | |
| SCHEMBL28560290 | 0.74 | ESR2 (0.36) | HTTESR2ESR1CYP2B6ALDH1A1 | |
| SCHEMBL28096487 | 0.74 | BACE1 (0.62) | BACE1HTTPDE4BPDE4APDE4C | |
| SCHEMBL1760592 | 0.73 | ESR2 (0.53) | BACE1HTTPDE4BPDE4APDE4C | |
| SCHEMBL28670383 | 0.73 | BACE1 (0.48) | BACE1HTTPDE4BPDE4APDE4C | |
| SCHEMBL27644465 | 0.73 | ALDH1A1 (0.50) | BACE1HTTPDE4BPDE4APDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0487524-A1 | METHOD AND APPARATUS FOR DETERMINING NON-TRIGLYCERIDES IN OILS. | LIBRA LAB INC (US) | 1992-06-03 | — | — | EP | claimed |
| EP-0487524-A4 | METHOD AND APPARATUS FOR DETERMINING NON-TRIGLYCERIDES IN OILS. | LIBRA LAB INC (US) | 1991-11-26 | — | — | EP | claimed |
| US-5055410-A | Colorimetric analysis;detecting reaction product of indicator and contaminants | LIBRA LABORATORIES, INC. (US) | 1991-10-08 | — | — | US | claimed |
| WO-1990010218-A1 | METHOD AND APPARATUS FOR DETERMINING NON-TRIGLYCERIDES IN OILS | LIBRA LABORATORIES, INC. (US) | 1990-09-07 | — | — | WO | claimed |
| EP-0487524-B1 | METHOD AND APPARATUS FOR DETERMINING NON-TRIGLYCERIDES IN OILS | LIBRA LAB INC (US) | 1995-05-10 | — | — | EP | disclosed |