Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 3/20 | 0.35 |
| ▸ | AKT2 | P31751 | 2/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | BRD2 | P25440 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24848661 | 0.77 | MAPT (0.39) | ESR2ESR1MAPTHTTLMNA | |
| SCHEMBL27770560 | 0.76 | ESR2 (0.45) | ESR2MAPTHTTLMNABRD4 | |
| SCHEMBL16901963 | 0.76 | BACE1 (0.41) | ESR2ESR1MAPTHTTLMNA | |
| SCHEMBL9254935 | 0.74 | BACE1 (0.44) | ESR2ESR1MAPTHTTLMNA | |
| SCHEMBL20873646 | 0.74 | MAPT (0.43) | ESR2MAPTHTTLMNABRD4 | |
| SCHEMBL22391489 | 0.73 | MAPT (0.48) | MAPTHTTLMNABRD4AKT2 | |
| SCHEMBL959273 | 0.73 | ALDH1A1 (0.44) | ESR2MAPTHTTLMNABRD4 | |
| SCHEMBL5547255 | 0.73 | MAPT (0.44) | ESR2MAPTHTTLMNABRD4 | |
| SCHEMBL1133458 | 0.72 | PSMB5 (0.46) | ESR2MAPTHTTLMNABRD4 | |
| SCHEMBL5551256 | 0.72 | MAPT (0.42) | ESR2MAPTHTTLMNABRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109535397-B | Stable organic light-emitting free radical polymer and OLED (organic light-emitting diode) device based on same | 吉林大学 | 2021-04-27 | — | — | CN | disclosed |