Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 19/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9254978 | 1.00 | ALOX5 (0.55) | ALOX5CYP2D6HRH3 | |
| SCHEMBL9255661 | 1.00 | ALOX5 (0.55) | ALOX5CYP2D6HRH3 | |
| SCHEMBL9307868 | 0.82 | ALOX5 (0.62) | ALOX5 | |
| SCHEMBL9310396 | 0.78 | ALOX5 (0.63) | ALOX5 | |
| SCHEMBL9310760 | 0.75 | ALOX5 (0.66) | ALOX5 | |
| SCHEMBL9022480 | 0.71 | ALOX5 (0.63) | ALOX5 | |
| SCHEMBL9256165 | 0.71 | ALOX5 (1.00) | ALOX5 | |
| SCHEMBL9138182 | 0.71 | ALOX5 (0.73) | ALOX5 | |
| SCHEMBL9135205 | 0.70 | ALOX5 (0.67) | ALOX5CYP2D6HRH3 | |
| SCHEMBL9138701 | 0.69 | ALOX5 (0.68) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5475009-A | Inhibit biosynthesis of leukotrienes | ABBOTT LABORATORIES (US) | 1995-12-12 | — | — | US | disclosed |