Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 20/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9310760 | 0.90 | ALOX5 (0.66) | ALOX5 | |
| SCHEMBL9310396 | 0.82 | ALOX5 (0.63) | ALOX5 | |
| SCHEMBL9254988 | 0.82 | ALOX5 (0.55) | ALOX5 | |
| SCHEMBL9254978 | 0.82 | ALOX5 (0.55) | ALOX5 | |
| SCHEMBL9255661 | 0.82 | ALOX5 (0.55) | ALOX5 | |
| SCHEMBL9135205 | 0.81 | ALOX5 (0.67) | ALOX5 | |
| SCHEMBL9307254 | 0.79 | ALOX5 (0.64) | ALOX5 | |
| SCHEMBL9256165 | 0.77 | ALOX5 (1.00) | ALOX5 | |
| SCHEMBL8953673 | 0.76 | ALOX5 (0.37) | ALOX5 | |
| Zd-2138 SCHEMBL1083603 | 0.74 | ALOX5 (1.00) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5354865-A | Enzyme inhibitor and inhibiting the leukotriene biosynthesis | ABBOTT LABORATORIES (US) | 1994-10-11 | — | — | US | disclosed |