Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10459921 | 0.87 | ALDH1A1 (0.68) | ALDH1A1L3MBTL1HTTPOLBLMNA | |
| SCHEMBL9249214 | 0.84 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1HTTGAAKDM4E | |
| SCHEMBL9256864 | 0.79 | CYP2C19 (0.52) | ALDH1A1HTTKDM4ESMN1; SMN2CYP1A2 | |
| SCHEMBL4283460 | 0.78 | ALDH1A1 (0.58) | ALDH1A1L3MBTL1HTTPOLBLMNA | |
| SCHEMBL9782499 | 0.78 | ALDH1A1 (0.61) | ALDH1A1L3MBTL1HTTPOLBLMNA | |
| Hydrochloric Acid SCHEMBL9621338 | 0.77 | ALDH1A1 (0.60) | ALDH1A1L3MBTL1HTTPOLBLMNA | |
| SCHEMBL9252776 | 0.75 | CYP2C19 (0.60) | ALDH1A1HTTLMNATSHRKDM4E | |
| Hydrochloric Acid SCHEMBL9249587 | 0.74 | CYP2C19 (0.59) | ALDH1A1HTTLMNATSHRKDM4E | |
| Hydrochloric Acid SCHEMBL15303081 | 0.74 | ALDH1A1 (0.54) | ALDH1A1L3MBTL1HTTPOLBLMNA | |
| SCHEMBL15307480 | 0.73 | ALDH1A1 (0.56) | ALDH1A1L3MBTL1HTTPOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5446146-A | Treatment of liver disorders | NIPPON CHEMIPHAR CO., LTD. (JP) | 1995-08-29 | — | — | US | disclosed |
| EP-0326379-B1 | Therapeutic agent for liver disease and piperazine derivatives | NIPPON CHEMIPHAR CO (JP) | 1994-06-01 | — | — | EP | disclosed |
| US-5070089-A | INHIBITION OF LIPID PEROXIDATION | NIPPON CHEMIPHAR CO., LTD. (JP) | 1991-12-03 | — | — | US | disclosed |
| EP-0326379-A2 | Therapeutic agent for liver disease and piperazine derivatives | NIPPON CHEMIPHAR CO., LTD. (JP) | 1989-08-02 | — | — | EP | disclosed |