Known targets — ChEMBL curated mechanism
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The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | AOC3 | Q16853 | 4/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | RGS12 | O14924 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL765762 | 0.91 | KDM4E (0.65) | KDM4EALDH1A1LMNAADRA2CADRA2A | |
| SCHEMBL2736710 | 0.91 | KDM4E (0.65) | KDM4EALDH1A1LMNAADRA2CADRA2A | |
| SCHEMBL28263575 | 0.91 | KDM4E (0.65) | KDM4EALDH1A1LMNAADRA2CADRA2A | |
| SCHEMBL1961679 | 0.91 | KDM4E (0.65) | KDM4EALDH1A1LMNAADRA2CADRA2A | |
| Benzene SCHEMBL28266518 | 0.91 | KDM4E (0.65) | KDM4EALDH1A1LMNAADRA2CADRA2A | |
| Hydrochloric Acid SCHEMBL29430219 | 0.88 | ALDH1A1 (0.67) | KDM4EALDH1A1LMNAADRA2CADRA2A | |
| SCHEMBL9504694 | 0.88 | KDM4E (0.62) | KDM4EALDH1A1LMNAADRA2CADRA2A | |
| Fluoride SCHEMBL28094990 | 0.88 | KDM4E (0.62) | KDM4EALDH1A1LMNAADRA2CADRA2A | |
| SCHEMBL9504702 | 0.88 | KDM4E (0.62) | KDM4EALDH1A1LMNAADRA2CADRA2A | |
| Phenyl Ethanol SCHEMBL7170311 | 0.81 | LMNA (0.56) | KDM4EALDH1A1LMNAADRA2CADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0421759-B1 | Method for producing 1-indanone derivatives | HOECHST CELANESE CORP (US) | 1995-06-07 | — | — | EP | claimed |