Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.65 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.65 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.60 |
| ▸ | RGS12 | O14924 | 1/20 | 0.60 |
| ▸ | GLA | P06280 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | HTR2A | P28223 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL765762 | 1.00 | KDM4E (0.65) | KDM4ELMNAADRA2CADRA2AHIF1A | |
| SCHEMBL1961679 | 1.00 | KDM4E (0.65) | KDM4ELMNAADRA2CADRA2AHIF1A | |
| SCHEMBL9504694 | 0.97 | KDM4E (0.62) | KDM4ELMNAADRA2CADRA2AHIF1A | |
| Hydrochloric Acid SCHEMBL29430219 | 0.97 | ALDH1A1 (0.67) | KDM4ELMNAADRA2CADRA2AHIF1A | |
| SCHEMBL9504702 | 0.97 | KDM4E (0.62) | KDM4ELMNAADRA2CADRA2AHIF1A | |
| Alcohol SCHEMBL9255166 | 0.91 | KDM4E (0.57) | KDM4ELMNAADRA2CADRA2AHIF1A | |
| SCHEMBL19757666 | 0.85 | CYP3A4 (0.58) | KDM4ELMNAADRA2CADRA2AHIF1A | |
| SCHEMBL17878528 | 0.85 | CYP3A4 (0.58) | KDM4ELMNAADRA2CADRA2AHIF1A | |
| SCHEMBL6839350 | 0.85 | KDM4E (0.46) | KDM4ELMNAADRA2CADRA2AHIF1A | |
| SCHEMBL21473258 | 0.84 | KDM4E (0.60) | KDM4ELMNAADRA2CADRA2AHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230295115-A1 | SUBSTITUTED ISOQUINOLINYLMETHYL AMIDES, ANALOGUES THEREOF, AND METHODS USING SAME | ARBUTUS BIOPHARMA CORP (CA) | 2023-09-21 | — | — | US | disclosed |
| US-11725010-B2 | Polyheterocyclic compounds as METTL3 inhibitors | STORM THERAPEUTICS LIMITED (GB) | 2023-08-15 | — | — | US | disclosed |
| US-20230192671-A1 | COMPOUNDS FOR THE TREATMENT OF SARS | PURDUE RESEARCH FOUNDATION | 2023-06-22 | — | — | US | disclosed |
| US-20230192671-A1 | COMPOUNDS FOR THE TREATMENT OF SARS | PURDUE RESEARCH FOUNDATION | 2023-06-22 | — | — | US | disclosed |
| WO-2023104209-A1 | METTL3 INHIBITOR COMPOUND | 上海昂阔医药有限公司 | 2023-06-15 | — | — | WO | disclosed |
| US-20230142606-A1 | PESTICIDALLY ACTIVE FUSED BICYCLIC HETEROAROMATIC AMINO COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2023-05-11 | — | — | US | disclosed |
| US-20230131903-A1 | PESTICIDALLY ACTIVE FUSED BICYCLIC HETEROAROMATIC COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2023-04-27 | — | — | US | disclosed |
| US-20220185789-A1 | PESTICIDALLY ACTIVE DIAZINE-AMIDE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2022-06-16 | — | — | US | disclosed |
| US-20220119329-A1 | Manganese Catalysts and Their Use in Hydrogenation of Ketones | UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS (GB) | 2022-04-21 | — | — | US | disclosed |
| EP-3956330-A1 | SUBSTITUTED 2-AMINO-PYRAZOLYL-[1,2,4]TRIAZOLO[1,5A] PYRIDINE DERIVATIVES AND USE THEREOF | The Johns Hopkins University (US) | 2022-02-23 | — | — | EP | disclosed |
| EP-0817770-B1 | NONPEPTIDES AS TACHYKININ ANTAGONISTS | WARNER LAMBERT CO (US) | 2002-02-27 | — | — | EP | disclosed |
| EP-0564924-B1 | 2-Oxoethyl derivatives as immunosuppressants | BAYER AG (US) | 1998-09-09 | — | — | EP | disclosed |
| EP-0817770-A1 | NONPEPTIDES AS TACHYKININ ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1998-01-14 | — | — | EP | disclosed |
| US-5686424-A | FOR TREATING INFLAMMATION | MILES INC. (US) | 1997-11-11 | — | — | US | disclosed |
| WO-1996029304-A1 | NONPEPTIDES AS TACHYKININ ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1996-09-26 | — | — | WO | disclosed |
| US-5554641-A | Nonpeptides as tachykinin antagonists | WARNER-LAMBERT COMPANY | 1996-09-10 | — | — | US | disclosed |
| EP-0608002-A1 | Optically active compounds | UNIVERSITY OF STRATHCLYDE (GB) | 1994-07-27 | — | — | EP | disclosed |
| EP-0564924-A2 | 2-Oxoethyl derivatives as immunosuppressants | Bayer Corporation (US) | 1993-10-13 | — | — | EP | disclosed |
| US-4959472-A | Process for preparing substantially pure diastereoisomers of tetrahydrofolic derivatives | UNIVERSITY OF STRATHCLYDE (GB) | 1990-09-25 | — | — | US | disclosed |
| EP-0266042-A2 | Optically active pteridine derivatives | University of Strathclyde (GB) | 1988-05-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230131903-A1 | PESTICIDALLY ACTIVE FUSED BICYCLIC HETEROAROMATIC COMPOUNDS | DDT, ACHE, GSTO1 | KDM4E 3772/4885LMNA 2308/4885ADRA2C 345/4885 |
| US-20230142606-A1 | PESTICIDALLY ACTIVE FUSED BICYCLIC HETEROAROMATIC AMINO COMPOUNDS | DDT, ACHE, DDC | KDM4E 3102/4885LMNA 3307/4885ADRA2C 413/4885 |
| US-20230295115-A1 | SUBSTITUTED ISOQUINOLINYLMETHYL AMIDES, ANALOGUES THEREOF, AND METHODS USING SAME | HCCS, HAVCR2, HDGF | KDM4E 692/4885LMNA 2574/4885ADRA2C 4466/4885 |
| US-20220185789-A1 | PESTICIDALLY ACTIVE DIAZINE-AMIDE COMPOUNDS | DDT, ACHE, NIT2 | KDM4E 2663/4885LMNA 2904/4885ADRA2C 1346/4885 |
| US-20230192671-A1 | COMPOUNDS FOR THE TREATMENT OF SARS | ACE2, ACE, SARS1 | KDM4E 3407/4885LMNA 2592/4885ADRA2C 1164/4885 |
| US-11725010-B2 | Polyheterocyclic compounds as METTL3 inhibitors | METTL3, DIMT1, TPMT | KDM4E 107/4885LMNA 2764/4885ADRA2C 4323/4885 |
| US-20220119329-A1 | Manganese Catalysts and Their Use in Hydrogenation of Ketones | CYC1, SCO2, MT-CO3 | KDM4E 2900/4885LMNA 319/4885ADRA2C 3053/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.