Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 4/20 | 0.81 |
| ▸ | PRCP | P42785 | 2/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9255302 | 1.00 | KCNH2 (0.81) | KCNH2PRCPSIGMAR1GRIN1GRIN2B | |
| SCHEMBL8555810 | 0.90 | KCNH2 (1.00) | KCNH2PRCPHTR2AHTR2CHTR2B | |
| SCHEMBL8554712 | 0.90 | KCNH2 (1.00) | KCNH2PRCPHTR2AHTR2CHTR2B | |
| SCHEMBL8556398 | 0.90 | KCNH2 (1.00) | KCNH2PRCPHTR2AHTR2CHTR2B | |
| SCHEMBL8864698 | 0.84 | KCNH2 (0.83) | KCNH2SIGMAR1HTR2AHTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL8864716 | 0.83 | KCNH2 (0.81) | KCNH2SIGMAR1HTR2AHTR2CHTR2B | |
| SCHEMBL8554225 | 0.81 | KCNH2 (0.83) | KCNH2HTR2AHTR2CHTR2B | |
| SCHEMBL8553316 | 0.81 | KCNH2 (0.83) | KCNH2HTR2AHTR2CHTR2B | |
| SCHEMBL8553978 | 0.81 | KCNH2 (0.83) | KCNH2 | |
| SCHEMBL8557736 | 0.81 | KCNH2 (0.83) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5380721-A | Aryl-fused and hetaryl-fused-2,4-diazepine and 2,4-diazocine antiarrhythmic agents | STERLING WINTHROP INC. (US) | 1995-01-10 | — | — | US | claimed |