Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 5/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.35 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9260855 | 0.88 | KDR (0.38) | HDAC6NPC1RAB9AMAPTADAM17 | |
| SCHEMBL9254836 | 0.84 | RXRA (0.48) | HDAC6NPC1RAB9AMAPTADAM17 | |
| SCHEMBL9263173 | 0.83 | RXRA (0.47) | HDAC6NPC1RAB9AMAPTADAM17 | |
| SCHEMBL9255197 | 0.82 | NPC1 (0.38) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL9260521 | 0.82 | HDAC6 (0.48) | HDAC6NPC1RAB9AMAPTGAA | |
| SCHEMBL9263178 | 0.82 | HDAC6 (0.46) | HDAC6NPC1RAB9AMEN1KMT2A | |
| SCHEMBL9264987 | 0.81 | ALOX5 (0.41) | MEN1KMT2ALMNASMN1; SMN2CA12 | |
| SCHEMBL9259605 | 0.77 | NR4A2 (0.53) | HDAC6NPC1RAB9AKMT2AMAPT | |
| SCHEMBL9263275 | 0.77 | NPC1 (0.48) | HDAC6NPC1RAB9AMEN1KMT2A | |
| SCHEMBL9263848 | 0.73 | APEX1 (0.38) | HDAC6MEN1KMT2AMAPTADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5432195-A | Anticholesterol | NIPPON SHINYAKU COMPANY LIMITED (JP) | 1995-07-11 | — | — | US | disclosed |
| EP-0601181-A1 | BENZOFURAN DERIVATIVE AND PHARMACEUTICAL COMPOSITION | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1994-06-15 | — | — | EP | disclosed |